Anti-Streptolysin O titre (ASO)
Group A streptococci (Streptococcus pyogenes) produces streptolysin which is a cytolysin. Infected patients mount an immune response to streptolysin O which can be detected 1 week and peaks 2-4 weeks after the infection. In patients without complications or reinfections the anti-streptolysin O (ASO) titre falls to pre-infection levels within 6-12 months. Elevated ASO titres are seen in 80-85% of patients with rheumatic fever and 95% of patients with post-streptococcal glomerulonephritis. Indicated in Any condition associated with infection by streptococcus pyogenes e.g. rheumatic fever, nephritis, arthritis etc
| Tube | Serum Gel |
|---|---|
| ID | 12752 |
| Availability | Weekdays |
| Additional Information | Measurement can be useful diagnostically if recent infection with streptococci is known to be important in aetiology. Diseases include rheumatic fever, post streptococcal glomerulonephritis and scarlet fever. A rise in ASO titre above 408 U/mL is associated with recent strep infection. Elevated ASO titres are seen in 80-85% of patients with rheumatic fever and 95% of patients with post-streptococcal glomerulonephritis. |
| Turn Around | 7 days |
| Send to | Leeds General Infirmary Clinical Immunology Old Medical School Great George Street Leeds LS1 3EX |
| Collection Con | No restrictions |
| Frequency | Daily |
| Sample REQ | Blood |
| Ref. Range (Male) | <408 |
| Ref. Range (Female) | <408 |
| Ref. Range Notes | <408 IU/mL |
| Units | IU/mL |
| IP Acute TAT | - Contact Laboratory |
| IP Routine TAT | 7 days |
| GP Acute TAT | - Contact Laboratory |
| GP Routine TAT | 7 days |
| Telepath | ASO2L |
| ICE Codes | IASO |
