The Leeds Teaching Hospitals NHS Trust

C1q

C1q

Primary component of classical complement pathway. C1q levels are usually only measured in cases where CH50 is absent or the patient has an increased susceptibility to infection, with the excception of the identification of acquired angioedema. C1q deficiency is rare and associated with SLE and recurrent bacterial infections. In suspected deficiency haemolytic complement should be analysed first. C1q is usuful in the differential diagnosis of Aquired Angioedema (AAE).

Tube Serum Gel
ID 12817
Availability Weekdays
Additional Information A deficiency of C1q can lead to a reduced or absent CH50 value. Levels are also low in aquired C1 inhibitor deficiency and reduced in urticarial vasculitis. The sample must be frozen within 2h of collection. Please inform the laboratory prior to collecting the sample.
Turn Around Refer to relevant laboratory for up to date turn around times, allowing an additional 10 working days for samples processing, dispatch and reporting and validation of the results (estimated 28days)
Send to Samples should be sent to the department of Clinical Immunology at LGI who will refer to appropriate referral lab (Sheffield PRU)
Contact https://www.immqas.org.uk/pru.asp?S=348233353&C=1252&AID=51
Collection Con The sample must be frozen within 2h of collection. Please inform the laboratory prior to collecting the sample.
Frequency Referred to external laboratory
Sample REQ Blood
Ref. Range Notes See reference range on referral website
Units mg/L
IP Acute TAT - Contact Laboratory
IP Routine TAT 7 days
GP Acute TAT - Contact Laboratory
GP Routine TAT 7 days
Telepath C1Q1L
ICE Codes IC1Q