Lupus anticoagulant is a heterogenous group of auto antibodies, usually directed at phospholipids. The presence of lupus anticoagulants is generally accompanied by a raised APTT but the physiological effect is an increase in the risk of thrombosis. A Lupus anticoagulant screen consists of a coagulation screen including a second APTT reagent, Actin FS APTT and a Russells viper venom ratio.
|Tube||05 (CP) - Citrate|
|Additional Information||Testing CANNOT be performed if: 1). The patient is on unfractionated heparin. All positive screens require repeat in 12 weeks to demonstrate continuity. 2) DOACs - Dabigatran, Rivaroxaban and Apixaban may also influence LA.|
|Turn Around||7 days|
|Send to||Specialist Coagulation
Chancellor / Lincoln Wing Link Corridor
St James University Hospital
|Collection Con||2 x citrate samples (all citrate tubes must be filled to the line).
Samples must be processed within 6 hours of being taken.
Plasma samples must be double-spun to remove platelets.
|Ref. Range Notes||Results will be reported with numerical values for each assay and an interpretaive comment.
|ICE Codes||LAPFS, LLUPUS|