Lupus Anticoagulant
Lupus anticoagulant is a heterogenous group of auto antibodies, usually directed at phospholipids. The presence of lupus anticoagulants is generally accompanied by a raised APTT but the physiological effect is an increase in the risk of thrombosis. A Lupus anticoagulant screen consists of a coagulation screen including a second APTT reagent, Actin FS APTT and a Russells viper venom ratio.
| Tube | 05 (CP) - Citrate |
|---|---|
| ID | 29867 |
| Availability | Weekdays |
| Additional Information | Testing CANNOT be performed if: 1). The patient is on unfractionated heparin. All positive screens require repeat in 12 weeks to demonstrate continuity. 2) DOACs - Dabigatran, Rivaroxaban and Apixaban may also influence LA. |
| Turn Around | 7 days |
| Send to | Specialist Coagulation Chancellor / Lincoln Wing Link Corridor Pathology Block 32 St James University Hospital Beckett Street Leeds LS9 7TF |
| Contact | https://www.leedsth.nhs.uk/a-z-of-services/pathology-2/specialist-laboratory-medicine-slm/specialist-coagulation/?stage=Stage |
| Collection Con | 2 x citrate samples (all citrate tubes must be filled to the line). Samples must be processed within 6 hours of being taken. Plasma samples must be double-spun to remove platelets. |
| Sample REQ | Blood |
| Ref. Range Notes | Results will be reported with numerical values for each assay and an interpretaive comment. |
| Units | Positive/Negative |
| Telepath | LUP1J |
| ICE Codes | LAPFS, LLUPUS |
