Aldosterone
Raised in primary & secondary aldosteronism, very low sodium diet, pregnancy, and Bartter's syndrome. Decreased in CAH, aldosterone synthetase deficiency, very high sodium diet, Addison's disease, and hyporeninaemic hypoaldosteronism. Call the laboratory for advice on when this test is indicated.
| Tube | Serum or Lithium Heparin or EDTA plasma |
|---|---|
| ID | 12609 |
| Availability | Weekly |
| Additional Information | Investigation of unexplained hypokalaemia, particularly when associated with hypertension. Results should be interpreted in conjunction with plasma renin levels. Values decrease in the elderly, but can be very high in the neonate. All antihypertensive medications potentially interfere with aldosterone physiology. |
| Turn Around | 21 days |
| Send to | Specialist Laboratory Medicine Block 46 St James hospital Beckett Street Leeds LS9 7TF |
| Contact | 1132067043 |
| Advice | 01132064717, stephen.gibbons@nhs.net |
| Collection Con | Should be measured in recumbent patient on a normal diet. Green/black topped tube (NOT green/yellow) EDTA tube also acceptable. Instructions for lab staff: Consult a BMS if sample older than 24hrs. Centrifuge and separate plasma. Store in freezer. |
| Sample REQ | Blood |
| Ref. Range (Male) | 100-850 pmol/L on random samples |
| Ref. Range (Female) | 100-850 pmol/L on random samples |
| Ref. Range Notes | Na intake 100-150, K intake 50-100 mmol/day, Adults aged 20-40 yrs: 08.00h after overnight recumbancy; 100-450. Random samples taken during normal activities through the day; 100- 850. Values decrease significantly in the elderly (> 60 yrs). Values can be very high (>5000) in the neonate, but reduce rapidly. Adult ref. ranges are reached by age 10 yrs |
| Units | pmol/L |
| IP Routine TAT | 21 days, note if requesting both PRA and aldosterone and only one sample is received, our quoted TAT is 30 days. |
| Telepath | ALDO2J |
| ICE Codes | LALDO |
