Viral Neurological screen: CSF samples for diagnosis of neurological disease by PCR
The advent of PCR has made the diagnosis of viral meningitis easier. Viral culture is no longer necessary and PCR is a very sensitive and specific test. Patients with suspected viral meningitis (either based on clinical presentation or on CSF differential WCC count - which shows a predominantly lymphocytic pleocytosis) will be tested for HSV, VZV adenovirus and enteroviruses/Parechovirus by PCR. In the immunocompromised CMV, EBV, JC and HHV-6 are added if meningitis has to be ruled out.
Meningococcus and Pneumococcal PCR can also be tested if indicated.
|Tube||CSF sample - white topped universal|
|Additional Information||Investigation of viral meningitis and encephalitis
Multiplex PCR testing for viral targets
|Turn Around||3 days|
|Send to||LGI Microbiology Department|
|Collection Con||CSF sample in plain universal. A separate sample and request should be sent for testing.|
|IP Routine TAT||3 days|
|GP Routine TAT||3 days|