The Leeds Teaching Hospitals NHS Trust

Malignant Hyperthermia

The Malignant Hyperthermia (MH) Unit based at St James's Hospital is the national centre for the investigation of malignant hyperthermia and provides expertise in inherited muscle disorders. The unit is also a member of the European M.H. Group.

Malignant hyperthermia is an inherited disorder of the skeletal muscle in which patients develop a potentially fatal reaction to certain commonly used anaesthetic drugs.

The Unit provides:

  • a unique screening service for the United Kingdom, using both muscle biopsy and in-vitro laboratory tests and recently introduced DNA testing when appropriate
  • anaesthetic advice for patients known to be susceptible to the condition and who have a family history of MH
  • maintenance of a 24 hour "hot line" service available to anaesthetists and any other medically qualified person
  • active research unit including genetic DNA family studies


Malignant Hyperthermia Unit
Room 8.32A
Level 8
Clinical Sciences Building
St James’s University Hospital
Beckett Street
Leeds LS9 7TF


Contact Numbers

Direct Line: 0113 20 65270
Fax Number: 0113 20 64140
Emergency 24 hour Hot-Line: 07947 609601